SANUS. Volume 4, No. 12, October-December 2019, is a quarterly refereed publication edited by the University of Sonora through the Division of Biological and Health Sciences and the Department of Nursing. Blvd. Luis Encinas and Av. Rosales s/n, Col. Centro, C.P. 83000, Hermosillo, Sonora, Mexico; Tel. (662) 2592165, ext. 4700. www.sanus.uson.mx, email: sanus.enfermeria@unison.mx. Reservation of Rights to Exclusive Use No. 04-2018-021216431900-203, ISSN: 2448-6094, both granted by the National Copyright Institute. Responsible for the last update of this number is the Computer Science Department of the University of Sonora. Date of last modification December 30, 2019. Responsible Editor MCE María Alejandra Favela Ocaño. The opinions expressed by the authors do not necessarily reflect the position of the editors of the publication. Total or partial reproduction of the contents and images of this publication is authorized, as long as the source is fully cited.